[學(xué)位/學(xué)歷]
醫(yī)學(xué)碩士(中山大學(xué)光華口腔醫(yī)學(xué)院,,口腔臨床醫(yī)學(xué))
醫(yī)學(xué)博士(澳大利亞格里菲斯大學(xué)牙學(xué)院,口腔醫(yī)學(xué))
[學(xué)術(shù)簡(jiǎn)歷]
2009/03-2013/01 ?澳大利亞,,格里菲斯大學(xué)牙學(xué)院,,PhD,導(dǎo)師:A/Prof. Nigel A Morrison,、Prof. Newell Johnson,、Prof. Jin Gao
2006/09-2008/12 ?中山大學(xué)光華口腔醫(yī)學(xué)院,碩士,,導(dǎo)師:凌均棨教授
2001/09-2006/07 ?安徽醫(yī)科大學(xué)口腔醫(yī)學(xué)院,,學(xué)士
[工作經(jīng)歷]
2018.01-至今 ? ? ? ? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院 ? 副主任醫(yī)師
2015.06-2017.12 ? ?中山大學(xué)光華口腔醫(yī)學(xué)院附屬口腔醫(yī)院 ? ?講師、主治醫(yī)師
2013.02-2015.05 ? ?中山大學(xué)光華口腔醫(yī)學(xué)院附屬口腔醫(yī)院 ? ?助教,、醫(yī)師
[研究方向]
1.牙髓組織損傷修復(fù)及牙髓生物學(xué)研究
2.慢性根尖周炎局部骨破壞的臨床病理
3.口腔鱗癌局部骨侵襲的分子機(jī)制
[主持或參加科研項(xiàng)目]
1.國(guó)家自然科學(xué)基金青年項(xiàng)目,,81500839,7nd阻斷MCP-1趨化作用對(duì)破骨細(xì)胞介導(dǎo)的慢性根尖周炎骨吸收的抑制研究,,2016/01-2018/12,,18萬(wàn)元,在研,,主持,。
2. 廣東省衛(wèi)生廳醫(yī)學(xué)科研基金,B2014164,,特異性干擾MCP-1表達(dá)調(diào)控破骨細(xì)胞形成的作用研究,,2014/7-2016/7,1萬(wàn)元,,在研,,主持。
3. 中山大學(xué)青年教師培育計(jì)劃,,13ykpy41,,趨化因子MCP-1調(diào)控破骨細(xì)胞形成的作用研究,2013/12-2016/12,,15萬(wàn)元,,在研,主持,。
4.國(guó)家自然科學(xué)基金面上項(xiàng)目,,81570803,脂肪細(xì)胞來(lái)源的載體通過(guò)lncRNAs抑制骨髓間充質(zhì)干細(xì)胞成骨分化及其在老年骨質(zhì)疏松中的作用,,2016/01-2018/12,,70萬(wàn)元,在研,,第二,。
3. 國(guó)家自然科學(xué)基金面上項(xiàng)目,,81371133,lncRNA家族T-UCR介導(dǎo)Oct4轉(zhuǎn)錄調(diào)控?fù)p傷微環(huán)境中牙髓干細(xì)胞增殖和分化的分子機(jī)制,,2014/01-2017/12,,70萬(wàn)元,在研,,第三,。
[主要SCI論著]
1.Quan J, Morrison NA, Johnson NW, Gao J*. MCP-1 as a potential target to inhibit the bone invasion by oral squamous cell carcinoma. J Cell Biochem 2014; 115:1787-98.
2.Quan J, Elhousiny M, Johnson NW, Gao J*. Transforming growth factor-?1 treatment of oral cancer induces epithelial-mesenchymal transition and promotes bone invasion via enhanced activity of osteoclasts. Clin Exp Metastasis 2013; 30:659-70.
3.Quan J, Johnson NW, Zhou G, Parsons PG, Boyle GM, Gao J*. Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms. Cancer Metastasis Rev 2012; 31:209-19.
4.Quan J, Zhou C, Johnson NW, Francis G, Dahlstrom JE, Gao J*. Molecular pathways involved in crosstalk between cancer cells, osteoblasts and osteoclasts in the invasion of bone by oral squamous cell carcinoma. Pathology 2012; 44:221-7.
5.Gong Q#, Quan J#, Jiang H, Ling J*. Regulation of the Stromal Cell-derived Factor-1Alpha-CXCR4 Axis in Human Dental Pulp Cells. J Endod 2010; 36:1499-503.
6.Zhao H, Dong Y, Quan J, Smith R, Lam A, Weinstein S, Clements J, Johnson NW, Gao J*. Correlation of the expression of human kallikrein-related peptidases 4 and 7 with the prognosis in oral squamous cell carcinoma. Head Neck 2011; 33:566-72.
7.Khan UA, Hashimi SM, Khan S, Quan J, Bakr MM, Forwood MR, Morrison NM*. Differential Expression of Chemokines, Chemokine Receptors and Proteinases by Foreign Body Giant Cells (FBGCs) and Osteoclasts. J Cell Biochem 2014; 115:1290-8.
8.Mao X, Chen Z, Ling J, Quan J, Peng H, Xiao Y*. Methoxy-poly(ethylene glycol) modified poly(L-lactide) enhanced cell affinity of human bone marrow stromal cells by the upregulation of 1-cadherin and delta-2-catenin. Biomed Res Int 2014; 738239.
9.Zheng J, Mao X, Ling J*, He Q, Quan J, Jiang H. Association between serum level of magnesium and postmenopausal osteoporosis: a meta-analysis. Biol Trace Elem Res 2014; 159:8-14.
10.Zheng J, Mao X, Ling J*, He Q, Quan J. Low serum levels of zinc, copper, and iron as risk factors for osteoporosis: a meta-analysis.Biol Trace Elem Res 2014; 160:15-23.
11.Liu W, Gong Q, Ling J*, Zhang W, Liu Z, Quan J. Role of miR-424 on angiogenic potential in human dental pulp cells. J Endod 2014; 40:76-82.
[聯(lián)系方式]
地 址:廣州市越秀區(qū)陵園西路56號(hào)中山大學(xué)光華口腔醫(yī)學(xué)院附屬口腔醫(yī)院
電 話:020-87330599
傳 真:020-87330446
E-mail:[email protected];[email protected]
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